Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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5,851 – 5,865 of 60,541 results

5,851

Medchemexpress LLC HY-K0207 2 mL Medchemexpress, Anti-Flag Magnetic Beads CAS: Purity:>98%

Medchemexpress, HY-K0207 2 mL Anti-Flag Magnetic Beads CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,852

American Research Products Inc HUMAN SAG ELISA KIT

503007927 HUMAN SAG ELISA KIT

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5,853

Cayman Chemical DSDP, Purity: ≥98%, CAS: 1777807-64-3, 1 mg

A STING agonist; induces expression of an ISG54 luciferase reporter in HepAD38 cells that constitutively express human cGAS and STING; increases IFNB1, TNFA, and IL29 expression in HepG2 cells expressing wild-type human, but not C-terminal truncated human or mouse, STING, as well as in isolated human PBMCs at 50 µM; inhibits yellow fever, dengue, and Zika virus replication in THF fibroblasts at 50 µM

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5,854

Medchemexpress LLC Zaprinast | 37762-06-4 | 99.88% | 50 MG

Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5) that significantly increases cGMP levels in myocytes. It is also a G protein-coupled receptor 35 (GPR35) agonist, activating rat GPR35 strongly and human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.

Selective inhibitor of cGMP-selective Phosphodiesterase (PDE5).
Increases cGMP levels in myocytes.
G protein-coupled receptor 35 (GPR35) agonist.
Reduces vessel remodeling through antiproliferative and proapoptotic effects.
Enhances spatial memory and diminishes exploratory activity in mice.

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5,855

Medchemexpress LLC Broxaldine | 3684-46-6 | MFCD00865040 | 99.9% | 5 MG

Broxaldine (Brobenzoxaldine) is an antiprotozoal agent known to inhibit Clostridium difficile with a MIC value of 4 μM, and it also demonstrates antifungal effects. This product is for research use only.

Acts as an antiprotozoal agent
Inhibits Clostridium difficile
Exhibits antifungal properties
Purity of 99.88%
Supplied as a solid, white to off-white in appearance
Soluble in DMSO at 8.33 mg/mL
Specific storage conditions for powder and solutions are provided for stability

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5,856

Apexbio Technology LLC Alvelestat 848141-11-7 10mM (in 1mL DMSO)

Alvelestat (CAS 848141-11-7) is an orally bioavailable reversible inhibitor of neutrophil elastase (NE) It demonstrates high affinity for human NE exhibiting a Ki of 9 4 nM and over 600-fold selectivity compared to other serine proteases In whole blood cell-based and degranulation assays alvelestat shows pIC50 values of 7 36 7 32 and 7 3 respectively Preclinical studies indicate that alvelestat reduces NE-induced markers of lung injury such as hemoglobin and hydroxyproline levels and attenuates neutrophilic inflammation in models of acute lung injury as well as smoke-induced airway inflammation and emphysema These properties support its use in research on neutrophil-driven pulmonary diseases

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5,857

Medchemexpress LLC Animal-free IL-1 beta protein, mouse (His) | 10UG

Animal-Free IL-1 beta Protein, Mouse (His) is a recombinant mouse interleukin-1 beta (IL-1β) provided in an animal-free production format with a C-terminal His tag. It is supplied in small vial sizes suitable for in vitro research and biochemical characterization; molecular weight is approximately 17-19 kDa by SDS-PAGE.

Recombinant mouse IL-1 beta with C-terminal His tag.
Animal-free production to reduce animal-derived contaminants.
Available in 10 μg and 50 μg sizes for small-scale experiments.
Approximate molecular weight 17-19 kDa (reducing conditions).
Datasheet and safety data sheet available for handling and storage information.

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5,858

eMolecules 1269181-69-2 | Medchem Express | Nicodicosapent | 2mg | 446268806 | HY-17640 | 449.639 | C28H39N3O2

Ambeed | 18-((25-Dioxopyrrolidin-1-yl)oxy)-18-oxooctadecanoic acid | 100mg | 600838450 | A357864 | 146004-84-4 | 411.539 | C22H37NO6

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5,859

Cayman Chemical Indolicidin (trifluoroacetate salt), Purity: ≥98%, 5 mg

An antimicrobial peptide; active against MDR-EAEC (MICs = 32 µM for all); active against S. cerevisiae, T. beigelii, and C. albicans (MICs = 5-10, 2.5-5, and 5-10 µM, respectively); reduces viral replication of HIV-1 in MT-2 cells from 67-100 µg/ml; increases survival of MDR-EAEC-infected G. mellonella larvae

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5,860

Cayman Chemical NIBR0213, Purity: ≥98%, CAS: 1233332-14-3, 1 mg

A potent and selective S1P1 antagonist (IC50s = 2.5 and 2.0 nM for hS1P1 Ca2+ mobilization and in a GTPγS assay); inactive at S1P2, S1P3, and S1P4 receptors (IC50s = >20, >10, and >10 µM, respectively in a Ca2+ mobilization assay); reduces EAE disease severity in mice up to 26 days; induces pulmonary damage in rats when administered chronically

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5,861

Cayman Chemical Chlorin e6, Purity: ≥90%, CAS: 19660-77-6, 100 mg

A photosensitizer; active against S. aureus, P. aeruginosa, E. coli, and S. typhimurium when used at 20 µM in combination with PDT; induces tumor regression when combined with PDT in several sarcoma rat xenograft models at 5 and 10 mg/kg

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5,862

Medchemexpress LLC EphB3 protein, rat (HEK293, C-terminal His tag) | >95.0% | 50 UG

Recombinant rat EphB3 protein expressed in HEK293 cells and purified with a C-terminal His tag. Supplied as purified protein for research use; purity greater than 95% (reducing SDS-PAGE), suitable for biochemical and cell-based studies.

Recombinant rat EphB3 expressed in mammalian cells to preserve post-translational modifications.
C-terminal His tag for straightforward detection and purification.
High purity (>95%) suitable for biochemical and cell-based assays.
Available in small and larger pack sizes to accommodate experimental scale.
Suitable for receptor binding, signaling pathway, and antibody validation studies.

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5,863

Medchemexpress LLC HY-108577 5mg Medchemexpress, XE 991 dihydrochloride CAS:122955-13-9 Purity:>98%

Medchemexpress, HY-108577 5mg XE 991 dihydrochloride CAS:122955-13-9 XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 µM, 0.71 µM, 0.6 μM, and 0.98 µM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,864

Medchemexpress LLC Nickel(II) fluoride | 10028-18-9 | 99.0% | 96.69 g/mol | NiF2 | 5 G

Nickel(II) fluoride is an inorganic nickel fluoride used as a fluorinating agent and catalyst in surface treatments and specialty chemical syntheses. It is supplied as a high-purity solid suitable for research and industrial applications.

Chemical formula: NiF2.
CAS number: 10028-18-9.
Molecular weight: 96.69 g/mol.
Purity: 99.0%.
Typical packaging: 5 g, 10 g, 25 g, 50 g, 100 g.
Common uses: fluorinating agent, catalyst, surface treatment.

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5,865

Apexbio Technology LLC Protionamide, 500mg Cas# 14222-60-7

Protionamide 50mg. 1380087-89-7. MFCD28144505 Protionamide There are other sizes available. Please inqury us for quote.

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Bioactive Small Molecules

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Medchemexpress LLC HY-K0207 2 mL Medchemexpress, Anti-Flag Magnetic Beads CAS: Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Zaprinast | 37762-06-4 | 99.88% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Broxaldine | 3684-46-6 | MFCD00865040 | 99.9% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Animal-free IL-1 beta protein, mouse (His) | 10UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EphB3 protein, rat (HEK293, C-terminal His tag) | >95.0% | 50 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-108577 5mg Medchemexpress, XE 991 dihydrochloride CAS:122955-13-9 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nickel(II) fluoride | 10028-18-9 | 99.0% | 96.69 g/mol | NiF2 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More